Stochastically gating ion channels enable patterned spike firing through activity-dependent modulation of spike probability.

The transformation of synaptic input into patterns of spike output is a fundamental operation that is determined by the particular complement of ion channels that a neuron expresses. Although it is well established that individual ion channel proteins make stochastic transitions between conducting a...

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Bibliographic Details
Main Authors: Joshua T Dudman, Matthew F Nolan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000290&type=printable