Gastrin mediates cardioprotection through angiogenesis after myocardial infarction by activating the HIF-1α/VEGF signalling pathway

Gastrin mediates cardioprotection through angiogenesis after myocardial infarction by activating the HIF-1α/VEGF signalling pathway

Abstract Acute myocardial infarction (MI) is one of the leading causes of death in humans. Our previous studies showed that gastrin alleviated acute myocardial ischaemia–reperfusion injury. We hypothesize that gastrin might protect against heart injury after MI by promoting angiogenesis. An MI model...

Full description

Bibliographic Details
Main Authors: Rui Wang, Ziyue Zhang, Zaicheng Xu, Na Wang, Dezhong Yang, Zhi Zhao Liu, Qiao Liao, Xuewei Xia, Caiyu Chen, Jialing Shou, Liangpeng Li, Wei Eric Wang, Chunyu Zeng, Tianyang Xia, Hongyong Wang
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95110-7

Internet

https://doi.org/10.1038/s41598-021-95110-7

Similar Items