Delineation of the role of chromatin assembly and the Rtt101Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast.

Delineation of the role of chromatin assembly and the Rtt101Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast.

The DNA damage checkpoint is activated in response to DNA double-strand breaks (DSBs). We had previously shown that chromatin assembly mediated by the histone chaperone Asf1 triggers inactivation of the DNA damage checkpoint in yeast after DSB repair, also called checkpoint recovery. Here we show th...

Full description

Bibliographic Details
Main Authors: Li-Ting Diao, Chin-Chuan Chen, Briana Dennehey, Sangita Pal, Pingping Wang, Zie-Jie Shen, Angela Deem, Jessica K Tyler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5531559?pdf=render

Internet

http://europepmc.org/articles/PMC5531559?pdf=render

Similar Items