Characterization of influenza hemagglutinin interactions with receptor by NMR.

In influenza, the envelope protein hemagglutinin (HA) plays a critical role in viral entry by first binding to sialic acid receptors on the cell surface and subsequently mediating fusion of the viral and target membranes. In this work, the receptor binding properties of influenza A HA from different...

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Bibliographic Details
Main Authors: Christopher McCullough, Minxiu Wang, Lijun Rong, Michael Caffrey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3397988?pdf=render