Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression

Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression

Mortality from triple negative breast cancer (TNBC) is significantly higher in African American (AA) women compared to White American (WA) women emphasizing ethnicity as a major risk factor; however, the molecular determinants that drive aggressive progression of AA-TNBC remain elusive. Here, we dem...

Full description

Bibliographic Details
Main Authors: Sumit Siddharth, Sheetal Parida, Nethaji Muniraj, Shawn Hercules, David Lim, Arumugam Nagalingam, Chenguang Wang, Balazs Gyorffy, Juliet M Daniel, Dipali Sharma
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-12-01
Series:eLife
Subjects:
racial disparity
GLI1
Notch1
African American women
White American women
triple negative breast cancer
Online Access:https://elifesciences.org/articles/70729

Internet

https://elifesciences.org/articles/70729

Similar Items