Acute exposure to environmentally relevant levels of DDT alters muscle mitochondrial function in vivo in rats but not in vitro in L6 myotubes: A pilot study

Acute exposure to environmentally relevant levels of DDT alters muscle mitochondrial function in vivo in rats but not in vitro in L6 myotubes: A pilot study

Under insulin-stimulated conditions, skeletal muscle is the largest glucose consumer in the body. Mitochondrial dysfunction and damage to this tissue from oxidative stress are linked to the pathogenesis of type 2 diabetes. Environmental exposure to dichlorodiphenyltrichloroethane (DDT) and its metab...

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Bibliographic Details
Main Authors: Lucia Chehade, Hannah Khouri, Julie Malatier--Ségard, Audrey Caron, Jean-François Mauger, Natalie Ann Chapados, Céline Aguer
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Toxicology Reports
Subjects:
Dichlorodiphenyltrichloroethane
Glucose uptake
Glycolysis
Mitochondrial function
Oxidative stress
Persistent organic pollutants
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750022000348

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http://www.sciencedirect.com/science/article/pii/S2214750022000348

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