Long-term administration of olanzapine induces adiposity and increases hepatic fatty acid desaturation protein in female C57BL/6J mice

Long-term administration of olanzapine induces adiposity and increases hepatic fatty acid desaturation protein in female C57BL/6J mice

Objective(s): Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure. In addition, we investigated the hepatic fatty acid effects of ola...

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Bibliographic Details
Main Authors: Po-Hsun Hou, Geng-Ruei Chang, Chin-Pin Chen, Yen-Ling Lin, I-Shuan Chao, Ting-Ting Shen, Frank Mao
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Adiposity
Insulin
Olanzapine
Stearoyl-CoA desaturase-1- (SCD-1)
Triglyceride
Online Access:http://ijbms.mums.ac.ir/article_10615_6c547c4dfc213a36d7048873bc4843e0.pdf

Internet

http://ijbms.mums.ac.ir/article_10615_6c547c4dfc213a36d7048873bc4843e0.pdf

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