PPM1D Knockdown Suppresses Cell Proliferation, Promotes Cell Apoptosis, and Activates p38 MAPK/p53 Signaling Pathway in Acute Myeloid Leukemia

Objectives: This study was to explore the effect of protein phosphatase, Mg 2+ /Mn 2+ dependent 1D knockdown on proliferation and apoptosis as well as p38 MAPK/p53 signaling pathway in acute myeloid leukemia. Methods: The expression of protein phosphatase, Mg 2+ /Mn 2+ dependent 1D was detected in a...

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Bibliographic Details
Main Authors: Bin Li MD, Jie Hu MD, Di He BS, Qi Chen MD, Suna Liu BS, Xiaoling Zhu MD, Meijia Yu MD
Format: Article
Language:English
Published: SAGE Publishing 2020-07-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/1533033820942312