Hinge region mediates signal transmission of luteinizing hormone and chorionic gonadotropin receptor

Hinge region mediates signal transmission of luteinizing hormone and chorionic gonadotropin receptor

Luteinizing hormone-choriogonadotropin receptor (LHCGR), a class A G protein-coupled receptor (GPCR), plays a pivotal role in the maturation of reproductive organs and embryonic development. Compared with other GPCRs, the subfamily of LHCGR has a large extracellular domain (ECD) to interact with gly...

Full description

Bibliographic Details
Main Authors: Xinheng He, Jia Duan, Yujie Ji, Lifen Zhao, Hualiang Jiang, Yi Jiang, H. Eric Xu, Xi Cheng
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Glycoprotein hormone receptors
G protein-coupled receptors
Molecular dynamics simulation
Protein dynamics
Evolutionary analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022005335

Internet

http://www.sciencedirect.com/science/article/pii/S2001037022005335

Similar Items