Favipiravir, an antiviral drug, in combination with tamoxifen exerts synergistic effect in tamoxifen-resistant breast cancer cells via hTERT inhibition
Abstract Tamoxifen (TAM) is one of the most successful treatments for breast cancer; however, TAM resistance continues to be a significant barrier. TAM resistance has been reported to be associated with increased expression of human telomerase reverse transcriptase (hTERT). This enzyme shares struct...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-51977-w |