Immune infiltration, aggressive pathology, and poor survival outcomes in RECQL helicase deficient breast cancers

Immune infiltration, aggressive pathology, and poor survival outcomes in RECQL helicase deficient breast cancers

RECQL is essential for genomic stability. Here, we evaluated RECQL in 449 pure ductal carcinomas in situ (DCIS), 152 DCIS components of mixed DCIS/invasive breast cancer (IBC) tumors, 157 IBC components of mixed DCIS/IBC and 50 normal epithelial terminal ductal lobular units (TDLUs). In 726 IBCs, CD...

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Détails bibliographiques
Auteurs principaux: Ayat Lashen, Abdulbaqi Al-Kawaz, Jennie N Jeyapalan, Shatha Alqahtani, Ahmed Shoqafi, Mashael Algethami, Michael Toss, Andrew R Green, Nigel P Mongan, Sudha Sharma, Mohammad R Akbari, Emad A Rakha, Srinivasan Madhusudan
Format: Article
Langue:English
Publié: Elsevier 2024-01-01
Collection:Neoplasia: An International Journal for Oncology Research
Sujets:
RECQL
CD8
FOXP3
IL17
PDL1
PD1
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S1476558623000805

Internet

http://www.sciencedirect.com/science/article/pii/S1476558623000805

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