Pro-apoptotic properties and mitochondrial functionality in platelet-like-particles generated from low Aspirin-incubated Meg-01 cells

Pro-apoptotic properties and mitochondrial functionality in platelet-like-particles generated from low Aspirin-incubated Meg-01 cells

Long-term therapy with low Aspirin (ASA) dose is basis to prevent thrombotic acute events. However, the anti-platelet mechanisms of ASA remain not completely known. The aim was to analyze if in vitro exposure of human megakaryocytes to low ASA concentration may alter the apoptotic features of the ne...

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Bibliographic Details
Main Authors: Gala Freixer, Khaoula Zekri-Nechar, José J. Zamorano-León, Carlos Hugo-Martínez, Nora V Butta, Elena Monzón, María-José Recio, Manel Giner, Antonio López-Farré
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Platelets
Subjects:
apoptosis
aspirin
megakaryocytes
mitochondria
nitric oxide
platelets
Online Access:http://dx.doi.org/10.1080/09537104.2020.1839637

Internet

http://dx.doi.org/10.1080/09537104.2020.1839637

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