The Regulatory Roles of Chemerin-Chemokine-Like Receptor 1 Axis in Placental Development and Vascular Remodeling During Early Pregnancy

The Regulatory Roles of Chemerin-Chemokine-Like Receptor 1 Axis in Placental Development and Vascular Remodeling During Early Pregnancy

Chemerin is an adipokine that regulates metabolism in pregnancy. An elevation of serum chemerin level is associated with pregnancy complications. Consistently, we demonstrated that the chemerin expression was increased in placenta of preeclamptic patients at deliveries. The G protein-coupled recepto...

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Bibliographic Details
Main Authors: Qingqing Zhang, Zhonglin Xiao, Cheuk-Lun Lee, Yong-Gang Duan, Xiujun Fan, William S. B. Yeung, Philip C. N. Chiu, Jian V. Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chemerin
CMKLR1
placental development
trophoblast invasion
spiral artery remodeling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.883636/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.883636/full

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