MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels

Summary: MASTL is a mitotic accelerator with an emerging role in breast cancer progression. However, the mechanisms behind its oncogenicity remain largely unknown. Here, we identify a previously unknown role and eminent expression of MASTL in stem cells. MASTL staining from a large breast cancer pat...

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Bibliographic Details
Main Authors: Elisa Närvä, Maria E. Taskinen, Sergio Lilla, Aleksi Isomursu, Mika Pietilä, Jere Weltner, Jorma Isola, Harri Sihto, Heikki Joensuu, Sara Zanivan, Jim Norman, Johanna Ivaska
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007301