Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic Value

Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic Value

Colorectal liver metastases (CRLMs) are clinically heterogeneous lesions with poor prognosis. Genetic alterations play a crucial role in their progression. The traditional Fong clinical risk score (Fong-CRS) is commonly used for risk stratification and prognosis prediction. By identifying the genomi...

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Bibliographic Details
Main Authors: Xuanwen Bao, Kun Wang, Ming Liu, Bin Li, Hongwei Wang, Kemin Jin, Xiaoluan Yan, Hangyu Zhang, Quan Bao, Da Xu, Lijun Wang, Wei Liu, Yanyan Wang, Juan Li, Lijuan Liu, Weijia Fang, Baocai Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
colorectal liver metastases
genomic landscape
prognostics
overall survival
mutation signature
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.760618/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.760618/full

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