Double crosslinked biomimetic composite hydrogels containing topographical cues and WAY-316606 induce neural tissue regeneration and functional recovery after spinal cord injury

Double crosslinked biomimetic composite hydrogels containing topographical cues and WAY-316606 induce neural tissue regeneration and functional recovery after spinal cord injury

Spinal cord injury (SCI) is an overwhelming and incurable disabling condition, for which increasing forms of multifunctional biomaterials are being tested, but with limited progression. The promising material should be able to fill SCI-induced cavities and direct the growth of new neurons, with effe...

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Bibliographic Details
Main Authors: Xingchang Zhao, Xianzhe Lu, Kai Li, Shiqiang Song, Zhaohui Luo, Chuanchuan Zheng, Chengliang Yang, Xiumei Wang, Liqiang Wang, Yujin Tang, Chong Wang, Jia Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-06-01
Series:Bioactive Materials
Subjects:
Spinal cord injury
3D printing
PCL oriented fibers
WAY-316606
Wnt/β-catenin signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22005187

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http://www.sciencedirect.com/science/article/pii/S2452199X22005187

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