Membrane Attack Complex C5b-9 Promotes Renal Tubular Epithelial Cell Pyroptosis in Trichloroethylene-Sensitized Mice

Membrane Attack Complex C5b-9 Promotes Renal Tubular Epithelial Cell Pyroptosis in Trichloroethylene-Sensitized Mice

Trichloroethylene (TCE), a commonly used organic solvent, is known to cause trichloroethylene hypersensitivity syndrome (THS), also called occupational medicamentosa–like dermatitis due to TCE (OMDT) in China. OMDT patients presented with severe inflammatory kidney damage, and we have previously sho...

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Bibliographic Details
Main Authors: Feng Wang, Meng Huang, Yican Wang, Yiting Hong, Dandan Zang, Chunjun Yang, Changhao Wu, Qixing Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
trichloroethylene
membrane attack complex
renal tubular epithelial cell
pyroptosis
NLRP3 inflammasome
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.877988/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.877988/full

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