Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium

Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium

The retinal pigment epithelium (RPE) is progressively degenerated during age-related macular degeneration (AMD), one of the leading causes of irreversible blindness, which clinical hallmark is the buildup of sub-RPE extracellular material. Clinical observations indicate that Zn dyshomeostasis can in...

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Bibliographic Details
Main Authors: Ana Álvarez-Barrios, Lydia Álvarez, Enol Artime, Montserrat García, Imre Lengyel, Rosario Pereiro, Héctor González-Iglesias
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Nutrition
Subjects:
retinal pigment epithelium
cell culture
sub-RPE deposits
AMD in vitro model
zinc dyshomeostasis
physical barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1124987/full

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https://www.frontiersin.org/articles/10.3389/fnut.2023.1124987/full

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