Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model

Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model

Abstract Background Epidemiological studies have related desert dust events to increased respiratory morbidity and mortality. Although the Sahara is the largest source of desert dust, Saharan dust (SD) has been barely examined in toxicological studies. Here, we aimed to assess the NLRP3 inflammasome...

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Bibliographic Details
Main Authors: Gerrit Bredeck, Jochen Dobner, Burkhard Stahlmecke, Khanneh Wadinga Fomba, Hartmut Herrmann, Andrea Rossi, Roel P. F. Schins
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Particle and Fibre Toxicology
Subjects:
African dust
Lung inflammation
Alveolar epithelium
In vitro
Endotoxin
Online Access:https://doi.org/10.1186/s12989-023-00550-w

Internet

https://doi.org/10.1186/s12989-023-00550-w

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