Influence of metformin therapy and treatment with an allosteric luteinizing hormone agonist and chorionic gonadotropin on spermatogenesis in male rats with obesity

BACKGROUND: In men, obesity is accompanied by a complex of metabolic and hormonal disorders, which leads to androgen deficiency and impaired spermatogenesis. Antidiabetic drugs, including metformin (MF), and luteinizing hormone receptor (LHR) agonists, which activate testicular steroidogenesis, can...

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Bibliographic Details
Main Authors: K. V. Derkach, I. Yu. Morina, L. V. Bayunova, A. A. Bakhtuykov, E. A. Didenko, V. N. Sorokoumov, I. V. Romanova, A. O. Shpakov
Format: Article
Language:English
Published: Endocrinology Research Centre 2023-11-01
Series:Ожирение и метаболизм
Subjects:
Online Access:https://www.omet-endojournals.ru/jour/article/view/13018