Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

Summary: This study addresses the roles of nuclear receptor corepressor 2 (NCOR2) in prostate cancer (PC) progression in response to androgen deprivation therapy (ADT). Reduced NCOR2 expression significantly associates with shorter disease-free survival in patients with PC receiving adjuvant ADT. Ut...

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Bibliographic Details
Main Authors: Mark D. Long, Justine J. Jacobi, Prashant K. Singh, Gerard Llimos, Sajad A. Wani, Aryn M. Rowsam, Spencer R. Rosario, Marlous Hoogstraat, Simon Linder, Jason Kirk, Hayley C. Affronti, Andries Bergman, Wilbert Zwart, Moray J. Campbell, Dominic J. Smiraglia
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Cell Reports
Subjects:
neuroendocrine prostate cancer
recurrent prostate cancer
epigenome
NCOR2
patient-derived xenograft
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472101603X

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http://www.sciencedirect.com/science/article/pii/S221112472101603X

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