Physicochemical property distributions for accurate and rapid pairwise protein homology detection

<p>Abstract</p> <p>Background</p> <p>The challenge of remote homology detection is that many evolutionarily related sequences have very little similarity at the amino acid level. Kernel-based discriminative methods, such as support vector machines (SVMs), that use vecto...

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Bibliographic Details
Main Authors: Oehmen Christopher S, Ratuiste Kyle G, Webb-Robertson Bobbie-Jo M
Format: Article
Language:English
Published: BMC 2010-03-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/145