Gene methylation of CADM1 and MAL identified as a biomarker of high grade anal intraepithelial neoplasia
Abstract Human papillomavirus (HPV) is detected in up to 96% of anal squamous cell cancers, where screening programs needed. However, the best methodology is still undetermined. Host DNA methylation markers CADM1, MAL and miR124 have been identified in cervical disease, but not anal disease. Anal sw...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-07258-5 |