Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers.

Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers.

The development of insulin resistance (IR) in mouse models of obesity and type 2 diabetes mellitus (DM) is characterized by progressive accumulation of inflammatory macrophages and subpopulations of T cells in the visceral adipose. Regulatory T cells (Tregs) may play a critical role in modulating ti...

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Bibliographic Details
Main Authors: Jeffrey Deiuliis, Zubair Shah, Nilay Shah, Bradley Needleman, Dean Mikami, Vimal Narula, Kyle Perry, Jeffrey Hazey, Thomas Kampfrath, Madhukar Kollengode, Qinghua Sun, Abhay R Satoskar, Carey Lumeng, Susan Moffatt-Bruce, Sanjay Rajagopalan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3027666?pdf=render

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http://europepmc.org/articles/PMC3027666?pdf=render

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