Exercise Inhibits Doxorubicin-Induced Damage to Cardiac Vessels and Activation of Hippo/YAP-Mediated Apoptosis

Exercise Inhibits Doxorubicin-Induced Damage to Cardiac Vessels and Activation of Hippo/YAP-Mediated Apoptosis

Dose-related cardiomyopathy is a major side effect following doxorubicin (Dox). To investigate whether exercise (Ex)-induced vasculogenesis plays a role in reducing Dox-induced cardiotoxicity, GFP<sup>+</sup> bone marrow (BM) cells from GFP transgenic mice were transplanted into wild-typ...

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Bibliographic Details
Main Authors: Rong-Hua Tao, Masato Kobayashi, Yuanzheng Yang, Eugenie S. Kleinerman
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
doxorubicin
cardiotoxicity
exercise
BM stem cells
endothelial cells
pericytes
Online Access:https://www.mdpi.com/2072-6694/13/11/2740

Internet

https://www.mdpi.com/2072-6694/13/11/2740

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