Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zinc
Zinc is an important component of cellular antioxidant defenses and dysregulation of zinc homeostasis is a risk factor for coronary heart disease and ischemia/reperfusion injury. Intracellular homeostasis of metals, such as zinc, iron and calcium are interrelated with cellular responses to oxidative...
Main Authors: | Matthew J. Smith, Fan Yang, Alexander Griffiths, Alexander Morrell, Sarah J. Chapple, Richard C.M. Siow, Theodora Stewart, Wolfgang Maret, Giovanni E. Mann |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231723001131 |
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