Anti-amnesic effects of withaferin A, a steroidal lactone isolated from Withania adpressa, on scopolamine-induced memory impairment in mice

Anti-amnesic effects of withaferin A, a steroidal lactone isolated from Withania adpressa, on scopolamine-induced memory impairment in mice

Natural secondary metabolites have long served as sources of drugs against various health disorders, among them neurodegenerative diseases especially Alzheimer’s disease (AD). Withanolides, isolated from Withania species, have shown acetylcholinesterase inhibition activity and their neuroprotective...

Full description

Bibliographic Details
Main Authors: Widad Ben Bakrim, Laila El Bouzidi, Houria Manouze, Jawhar Hafsa, Mansour Sobeh, Saadia Ba-M'hamed, Khalid Bekkouche, Lamfeddal Kouisni
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Arabian Journal of Chemistry
Subjects:
Alzheimer's disease
Withania adpressa
Withaferin A
Anticholinesterase activity
Anti-amnestic effect
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522100544X

Internet

http://www.sciencedirect.com/science/article/pii/S187853522100544X

Similar Items