The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ.

Capsaicin is a natural compound present in chili and red peppers and the responsible of their spicy flavor. It has recently provoked interest because of its antitumoral effects in many cell types although its action mechanism is not clearly understood. As metabolic dysregulation is one of the hallma...

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Bibliographic Details
Main Authors: Alicia Bort, Belén G Sánchez, Elena Spínola, Pedro A Mateos-Gómez, Nieves Rodríguez-Henche, Inés Díaz-Laviada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211420