Identification of heptapeptides targeting a lethal bacterial strain in septic mice through an integrative approach

Abstract Effectively killing pathogenic bacteria is key for the treatment of sepsis. Although various anti-infective drugs have been used for the treatment of sepsis, the therapeutic effect is largely limited by the lack of a specific bacterium-targeting delivery system. This study aimed to develop...

Full description

Bibliographic Details
Main Authors: Xiaoyan Zhang, Shan Li, Haihua Luo, Shuyue He, Huangda Yang, Lei Li, Tian Tian, Qizheng Han, Jiacong Ye, Chenyang Huang, Aihua Liu, Yong Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01035-6