Association of CYP3A5 (6986A>G) gene polymorphism with the effectiveness of anti-inflammatory therapy in children with bronchial asthma

Inhaled glucocorticosteroids are the main drugs used to control bronchial asthma in children. P450-cytochrome of  3A (CYP3A) family is involved in  their metabolism. CYP3A5-isoenzyme plays the leading role in  the respiratory tract. We described 6986A>G polymorphism in the CYP3A5 gene encodin...

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Bibliographic Details
Main Authors: A. K. Zastrozhina, I. N. Zakharova, D. A. Sychev, E. A. Grishina, K. A. Ryzhikova
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2019-06-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/895