Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma

Abstract Background Neoadjuvant immune checkpoint blockade (ICB) combined with chemoradiotherapy offers high pathologic complete response (pCR) rate for patients with locally advanced esophageal squamous cell carcinomas (ESCC). But the dynamic tumor immune microenvironment modulated by such neoadjuv...

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Bibliographic Details
Main Authors: Dan-Dan Zheng, Yu-Ying Li, Xiao-Yi Yuan, Jiang-Li Lu, Mei-Fang Zhang, Jia Fu, Chris Zhiyi Zhang
Format: Article
Language:English
Published: BMC 2024-05-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-024-12406-3