CTNNB1 Knockdown Inhibits Cell Proliferation and Aldosterone Secretion Through Inhibiting Wnt/β-Catenin Signaling in H295R Cells
Aldosterone-producing adenomas (APA) is one of the causative factors of primary aldosteronism. Previous studies have suggested that there are somatic CTNNB1 mutations in APA, but the specific mechanism of CTNNB1 mutation in APA tumorigenesis and aldosterone secretion remains unclear. In the present...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-12-01
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Series: | Technology in Cancer Research & Treatment |
Online Access: | https://doi.org/10.1177/1533033820979685 |