Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer

Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer

Abstract Background The theory of field effect suggests that the tumor-adjacent area, besides histopathologically normal, undergoes genetic and epigenetic changes that can eventually affect epithelial homeostasis, predisposing the patient to cancer development. One of the many molecular changes desc...

Full description

Bibliographic Details
Main Authors: Camile B. Lopes, Leandro L. Magalhães, Carolina R. Teófilo, Ana Paula N. N. Alves, Raquel C. Montenegro, Massimo Negrini, Ândrea Ribeiro-dos-Santos
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
Oral cancer
Field cancerization
miRNAs
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s12885-018-4631-z

Internet

http://link.springer.com/article/10.1186/s12885-018-4631-z

Similar Items