SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions

SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions

Abstract Despite the many approaches to study differential splicing from RNA-seq, many challenges remain unsolved, including computing capacity and sequencing depth requirements. Here we present SUPPA2, a new method that addresses these challenges, and enables streamlined analysis across multiple co...

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Bibliographic Details
Main Authors: Juan L. Trincado, Juan C. Entizne, Gerald Hysenaj, Babita Singh, Miha Skalic, David J. Elliott, Eduardo Eyras
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Genome Biology
Subjects:
Differential splicing
Alternative splicing
RNA-seq
Uncertainty
Biological variability
Differentiation
Online Access:http://link.springer.com/article/10.1186/s13059-018-1417-1

Internet

http://link.springer.com/article/10.1186/s13059-018-1417-1

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