hnRNPU is required for spermatogonial stem cell pool establishment in mice

Summary: The continuous regeneration of spermatogonial stem cells (SSCs) underpins spermatogenesis and lifelong male fertility, but the developmental origins of the SSC pool remain unclear. Here, we document that hnRNPU is essential for establishing the SSC pool. In male mice, conditional loss of hn...

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Bibliographic Details
Main Authors: Yujiao Wen, Shumin Zhou, Yiqian Gui, Zeqing Li, Lisha Yin, Wenchao Xu, Shenglei Feng, Xixiang Ma, Shiming Gan, Mengneng Xiong, Juan Dong, Keren Cheng, Xiaoli Wang, Shuiqiao Yuan
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724004418