Alphavirus infection triggers antiviral RNAi immunity in mammals

Summary: RNA interference (RNAi) is a well-established antiviral immunity. However, for mammalian somatic cells, antiviral RNAi becomes evident only when viral suppressors of RNAi (VSRs) are disabled by mutations or VSR-targeting drugs, thereby limiting its scope as a mammalian immunity. We find tha...

Full description

Bibliographic Details
Main Authors: Jing Kong, Yuanyuan Bie, Wenting Ji, Jiuyue Xu, Bao Lyu, Xiaobei Xiong, Yang Qiu, Xi Zhou
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004527