Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced SteatosisSummary

Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced SteatosisSummary

Background & Aims: Cholesterol 25-hydroxylase (Ch25h), converting cholesterol to 25-hydroxycholesterol (25-HC), is critical in modulating cellular lipid metabolism and anti-inflammatory and antiviral activities. However, its role in nonalcoholic fatty liver disease remains unclear. Methods:...

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Bibliographic Details
Main Authors: Zeyu Dong, Fangzhou He, Xiaosong Yan, Yuanming Xing, Yuyang Lei, Jie Gao, Ming He, Dongmin Li, Liang Bai, Zuyi Yuan, John Y-J. Shyy
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
25-HC
Bile Acid Metabolism
Ch25h
CYP7A1
Hepatic Steatosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2100271X

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X2100271X

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