An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice

An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice

Interleukin (IL)-33, the most recent member of the IL family of cytokines, signals through the ST2 receptor. IL-33/ST2 signaling mediates antigen challenge-induced mechanical hyperalgesia in the joints and cutaneous tissues of immunized mice. The present study asked whether IL-33/ST2...

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Detalhes bibliográficos
Main Authors: D.A.C. Magro, M.S.N. Hohmann, S.S. Mizokami, T.M. Cunha, J.C. Alves-Filho, R. Casagrande, S.H. Ferreira, F.Y. Liew, F.Q. Cunha, W.A. Verri Jr
Formato: Artigo
Idioma:English
Publicado em: Associação Brasileira de Divulgação Científica 2013-08-01
Colecção:Brazilian Journal of Medical and Biological Research
Assuntos:
Interleukin-33
ST2
Pain
Nociception
Inflammation
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700601&lng=en&tlng=en

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