Proteomic and Metabolomic Analysis of Bone Marrow and Plasma from Patients with Extramedullary Multiple Myeloma Identifies Distinct Protein and Metabolite Signatures

Proteomic and Metabolomic Analysis of Bone Marrow and Plasma from Patients with Extramedullary Multiple Myeloma Identifies Distinct Protein and Metabolite Signatures

Multiple myeloma (MM) is an incurable haematological malignancy of plasma cells in the bone marrow. In rare cases, an aggressive form of MM called extramedullary multiple myeloma (EMM) develops, where myeloma cells enter the bloodstream and colonise distal organs or soft tissues. This variant is ass...

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Bibliographic Details
Main Authors: Katie Dunphy, Despina Bazou, Michael Henry, Paula Meleady, Juho J. Miettinen, Caroline A. Heckman, Paul Dowling, Peter O’Gorman
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
multiple myeloma
extramedullary multiple myeloma
extramedullary disease
proteomics
mass spectrometry
clinical proteomics
Online Access:https://www.mdpi.com/2072-6694/15/15/3764

Internet

https://www.mdpi.com/2072-6694/15/15/3764

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