Identification of α-fetoprotein as an autoantigen in juvenile Batten disease

Humoral autoimmunity against glutamic acid decarboxylase has been described in juvenile Batten disease patients and in the Cln3−/− mouse model. To obtain a more comprehensive understanding of the repertoire of antigens targeted, we examined the reactivity of Cln3−/− mouse sera to brain proteins from...

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Bibliographic Details
Main Authors: Julian A. Castaneda, David A. Pearce
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610700188X