AlphaFold2 models indicate that protein sequence determines both structure and dynamics

Abstract AlphaFold 2 (AF2) has placed Molecular Biology in a new era where we can visualize, analyze and interpret the structures and functions of all proteins solely from their primary sequences. We performed AF2 structure predictions for various protein systems, including globular proteins, a mult...

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Bibliographic Details
Main Authors: Hao-Bo Guo, Alexander Perminov, Selemon Bekele, Gary Kedziora, Sanaz Farajollahi, Vanessa Varaljay, Kevin Hinkle, Valeria Molinero, Konrad Meister, Chia Hung, Patrick Dennis, Nancy Kelley-Loughnane, Rajiv Berry
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14382-9