Epitope mapping of SARS-CoV-2 spike protein differentiates the antibody binding activity in vaccinated and infected individuals

Epitope mapping of SARS-CoV-2 spike protein differentiates the antibody binding activity in vaccinated and infected individuals

Previous studies have attempted to characterize the antibody response of individuals to the SARS-CoV-2 virus on a linear peptide level by utilizing peptide microarrays. These studies have helped to identify epitopes that have potential to be used for diagnostic tests to identify infected individuals...

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Bibliographic Details
Main Authors: Nathaniel Felbinger, David Trudil, Lawrence Loomis, Richard Ascione, Gregory Siragusa, Seiji Haba, Shruti Rastogi, Aidan Mucci, Mark Claycomb, Sebastian Snowberger, Brian Luke, Stephen Francesconi, Shirley Tsang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Virology
Subjects:
B-cell epitope
variant mutations
peptide microarray
IgG
SARS-CoV-2
spike protein
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2023.988109/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2023.988109/full

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