Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia.

Avian influenza viruses (AIVs) periodically cross species barriers and infect humans. The likelihood that an AIV will evolve mammalian transmissibility depends on acquiring and selecting mutations during spillover, but data from natural infection is limited. We analyze deep sequencing data from infe...

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Bibliographic Details
Main Authors: Louise H Moncla, Trevor Bedford, Philippe Dussart, Srey Viseth Horm, Sareth Rith, Philippe Buchy, Erik A Karlsson, Lifeng Li, Yongmei Liu, Huachen Zhu, Yi Guan, Thomas C Friedrich, Paul F Horwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008191