YAP1 Recognizes Inflammatory and Mechanical Cues to Exacerbate Benign Prostatic Hyperplasia via Promoting Cell Survival and Fibrosis

YAP1 Recognizes Inflammatory and Mechanical Cues to Exacerbate Benign Prostatic Hyperplasia via Promoting Cell Survival and Fibrosis

Abstract Chronic prostatic inflammation promotes cell survival and fibrosis, leading to benign prostatic hyperplasia (BPH) with aggravated urinary symptoms. It is investigated whether yes‐associated protein 1 (YAP1), an organ size controller and mechanical transductor, is implicated in inflammation‐...

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Bibliographic Details
Main Authors: Dongxu Lin, Changcheng Luo, Pengyu Wei, An Zhang, Mengyang Zhang, Xiaoliang Wu, Bolang Deng, Zhipeng Li, Kai Cui, Zhong Chen
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
benign prostatic hyperplasia
cytoskeleton remodeling
fibrosis
inflammation
yes‐associated protein 1
Online Access:https://doi.org/10.1002/advs.202304274

Internet

https://doi.org/10.1002/advs.202304274

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