Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor

Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor

Human immunodeficiency virus type 1 (HIV-1) is responsible for the majority of HIV infections worldwide, and we still lack a cure for this infection. Blocking the interaction of HIV-1 and its primary receptor CD4 is one strategy for identifying new anti-HIV-1 entry inhibitors. Here we report the dis...

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Bibliographic Details
Main Authors: Chaozai Zhang, Huijun Zhang, Lina S. Huang, Siyu Zhu, Yan Xu, Xing-Quan Zhang, Robert T. Schooley, Xiaohong Yang, Ziwei Huang, Jing An
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
HIV-1
entry inhibitor
CD4
virtual screening
3D-QSAR
Online Access:https://www.mdpi.com/1420-3049/23/11/3036

Internet

https://www.mdpi.com/1420-3049/23/11/3036

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