LncRNA MHRT Prevents Angiotensin II-Induced Myocardial Oxidative Stress and NLRP3 Inflammasome via Nrf2 Activation

LncRNA MHRT Prevents Angiotensin II-Induced Myocardial Oxidative Stress and NLRP3 Inflammasome via Nrf2 Activation

The development of angiotensin II (Ang II)-induced cardiomyopathies is reportedly mediated via oxidative stress and inflammation. Nuclear factor erythroid 2-related factor (Nrf2) is an important regulator of cellular antioxidant defense, and reactive oxygen species (ROS) can activate the NLRP3 infla...

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Bibliographic Details
Main Authors: Pinyi Liu, Xiaoming Dong, Chao Dong, Guowen Hou, Wenyun Liu, Xin Jiang, Ying Xin
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
nuclear factor erythroid 2-related factor 2
angiotensin II
oxidative stress
NLRP3 inflammasomes
long non-coding RNA MHRT
Online Access:https://www.mdpi.com/2076-3921/12/3/672

Internet

https://www.mdpi.com/2076-3921/12/3/672

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