A comparison of strategies for generating artificial replicates in RNA-seq experiments
Abstract Due to the overall high costs, technical replicates are usually omitted in RNA-seq experiments, but several methods exist to generate them artificially. Bootstrapping reads from FASTQ-files has recently been used in the context of other NGS analyses and can be used to generate artificial te...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-11302-9 |