A rapid and stable spontaneous reprogramming system of Spermatogonial stem cells to Pluripotent State

A rapid and stable spontaneous reprogramming system of Spermatogonial stem cells to Pluripotent State

Abstract Background The scarcity of pluripotent stem cells poses a major challenge to the clinical application, given ethical and biosafety considerations. While germline stem cells commit to gamete differentiation throughout life, studies demonstrated the spontaneous acquisition of pluripotency by...

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Bibliographic Details
Main Authors: Rui Wei, Xiaoyu Zhang, Xiaoxiao Li, Jian Wen, Hongyang Liu, Jiqiang Fu, Li Li, Wenyi Zhang, Zhen Liu, Yang Yang, Kang Zou
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cell & Bioscience
Subjects:
Cell fate
Feeder layer
Germline
Pluripotency
Reprogramming
Online Access:https://doi.org/10.1186/s13578-023-01150-z

Internet

https://doi.org/10.1186/s13578-023-01150-z

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