Secretion of autoimmune antibodies in the human subcutaneous adipose tissue.

The adipose tissue (AT) contributes to systemic and B cell intrinsic inflammation, reduced B cell responses and secretion of autoimmune antibodies. In this study we show that adipocytes in the human obese subcutaneous AT (SAT) secrete several pro-inflammatory cytokines and chemokines, which contribu...

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Bibliographic Details
Main Authors: Daniela Frasca, Alain Diaz, Maria Romero, Seth Thaller, Bonnie B Blomberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5955545?pdf=render