Naringin alleviates intestinal mucosal injury in mice with intra-abdominal infection by inhibiting non-canonical pyroptosis through P2X7 receptor

Naringin alleviates intestinal mucosal injury in mice with intra-abdominal infection by inhibiting non-canonical pyroptosis through P2X7 receptor

Objective To investigate the therapeutic efficacy and underlying mechanism of naringin (Ng) for intestinal mucosal injury in mice with intra-abdominal infection (IAI). Methods A mouse IAI model was established by intraperitoneal injection (i.p.) of lipopolysaccharide (LPS). Sixty-four healthy male m...

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Bibliographic Details
Main Authors: MA Yuan, DUAN Qianwen, DONG Xupeng
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2024-01-01
Series:陆军军医大学学报
Subjects:
abdominal infection
intestinal mucosal injury
non-canonical
caspase11
sepsis
Online Access:http://aammt.tmmu.edu.cn/html/202307058.htm

Internet

http://aammt.tmmu.edu.cn/html/202307058.htm

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